Telemedicine is rapidly growing with use of the internet, and the number of possibilities for its application is increasing with development of information technologies and digitization in many countries. Among all branches of medicine, psychiatry is particularly suitable for this type of service, because psychiatrist usually does not perform a physical examination of the patient, but rather professionals from other branches, as indicated by the psychiatrist. A professionally conducted, semi-structured interview in psychiatry is the basis of diagnostic and therapeutic work, but at its core is a therapeutic alliance between doctor and patient. In virtual work in psychiatry, many aspects are different than ever before. A number of studies show that patients are more satisfied with a telepsychiatry consultation than certain number of psychiatrists. Despite the numerous advantages of online consultation in psychiatry, including the availability of services to patients from remote areas, the possibility of consulting a psychiatrist in a native language and from a suitable cultural milieu, its application in certain indications is still a challenge. The efficiency and safety of its application implies compliance with local legal and regulatory requirements as well as technical requirements. This refers on the internet communication, ethical standards in diagnostic, therapeutic and research work, with the aim of making psychiatric online consultation as similar as possible to the one that takes place face-to-face.